Monoenoic fatty acids are abundant and particularly diversified in the pericarp (petroselinic, oleic, and cis- vaccenic acids). Aqueous extraction of its juvenile leaves has been used since the nineteenth century in traditional medicine for the treatment of respiratory disorders because of its expectorant and bronchospasmolytic effects ().Today its use was standardized by a Commission monograph of the … -Hedera helix grows better in shade during its juvenile phase, but once it has attained adult phase (reproductive) it is able to acclimate to very high light conditions (16). The entire pollen spectrum, 31 different types, was evaluated with the focus on the exact time of the volcanic eruption. In our original project of 2008 we attempted to solve the problem of the eruption time by analysing pollen mixed with falling down volcanic ash, and preserved intact in nasal cavities of the victims in Pompeii. Group B: received a single (i.p.) Among three samples of ash from nasal cavities of two children and an adult considered uncontaminated Hedera pollen was found in noses of both children but not of the adult. Documented information on the botany, biological activities, medicinal uses, and phytochemistry of C. paniculata was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. European Union herbal monograph on . Results: Histological assessment of dermal collagen bundles in the reticular layer showed that both 10% and 20% hedera helix creams, increased collagen bundle thickness significantly, compared to eucerin treated wounds (P. Introduction: The aim of the study was to evaluate the protective effect of Hedera helix (ivy) leaf extract on paracetamol-induced oxidative stress and renal toxicity in mouse model. The value of the diversity index was 0.79 and the polymorphic information index was 0.78. Published 13C NMR assignments of falcarinol and related compounds are corrected. According to clinical experiments, the effectiveness and tolerance of ivy preparations is good. Fraction 6 induces non-specific cytotoxicity via apoptosis and oxidative pathways demonstrated by the TUNEL and DPPH assays. Cussonia paniculata is a small tree widely used as herbal medicine throughout its distributional range in southern Africa. According to clinical experiments, the effectiveness and tolerance of ivy preparations is good. Results: In comparison to baseline, the following percentages of patients showed improved symptoms or were cured at treatment end: cough 92.2%; expectoration 94.2%; dyspnea 83.1%; respiratory pain 86.9%. This study showed that the bark, fruits, leaves, roots, and stems of C. paniculata are used as emetic, immune booster, and herbal medicine for dysmenorrhea, intestinal parasites and worms, mental problems, boils, shingles and skin diseases, indigestion and stomach complaints, sores, and wounds. Here is some basic information about Hedera helix and a list of ethnobotanical uses which includes medicinal uses and other uses of Hedera helix. Assessment report on Hedera helix L, leaf. The plants are traditionally used as anthelmintic, antitumor, and antiinflammatory agents. In each of the four symptoms at least 38% of the initially affected patients were completely free of complaints. This result is the first physical proof of Hedera as medicinal plant used for the treatment of respiratory tract disorders nearly 2000 years ago. No date of eruption could be suggested from this study. endstream endobj 95 0 obj <>stream Collagen is the main constituent of extracellular matrix. The amino acid composition of the Phaseolus lunatus β-lectin was not altered by β-elimination. (2,3) ... Community Herbal Monograph on Hedera helix L, leaf. Join ResearchGate to find the people and research you need to help your work. The plant extracts have exhibited potential anti - proliferative effect. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. Anti-Cancer Effect and Mechanisms of Action of Mikania cordata Plant Extract on MCF-7 Human Breast A... CHLOROPHYTUM COMOSUM (THUNBERG) JACQUES: A REVIEW, Himatanthus Willd. There were determined certain attributes of this marker such as the diversity index (DI) and polymorphism information content (PIC). The increase of granulometric size of cholesterol particle to Ø 1.60 mm decreased the amount of solubilized cholesterol but solubility preferences of the extracts were maintained. Externally it was used for burn wounds , calluses, cellulitis, inflammations, neuralgia, parasitic disorders, ulcers, rheumatic complaints and phlebitis. Most often the syrup containing of ivy leaf dry extract was used in doses twice a day for 2 ml or 4 ml. COMMON OR ENGLISH IVY: MEDICINAL BENEFITS OF HEDERA HELIX, USES AND HISTORY: IVY LEAF TISANE COMMON OR ENGLISH IVY, HEDERA HELIX. Introduction. The following aspects of Bacopa. View abstract. Medicinal plants and sustainable livelihood in Pauri district of Garhwal Himalaya, Uttarakhand, Indi... Phytochemical and microbiological evaluation of a local medicinal plant Bacopa monnieri (l.) Penn. Although it has been reported that HDC has anti-inflammatory characteristics, limited data is present regarding this, ... Ivy is a common name for Hedera L. species grown as ornamental plants and house plants throughout the world [22][23][24]. Measurements of viscosity and surface activity on phase boundary were performed. Subtilisin treatment of the Alocasia macrorrhizos β-lectin removes 80% of the protein and the material remaining after enzymic treatment retains the capacity to bind to the Yariv artificial antigen. Pharmacokinetic parameters such as t max , c max and AUC of the selected formulations and oral dosing were significantly different (P < 0.01). Non-medicinal Ingredients – Original Honey Flavour: Citric acid, flavour, potassium sorbate, purified water, sorbitol (each 5 mL dose contains 1.93 g of sorbitol as sugar substitute), xantham gum. Actually, a very limited information exists about application of DNA markers in Hedera helix . Introduction: Common ivy ( Hedera helix ) is a plant used successfully in the treatment of various ailments. Until today, the efficacy and safety of ivy leaf preparations has been demonstrated in a variety of controlled clinical studies and non-interventional studies. I °N@ѦTð(c‹®LÖ ŒO¼ÌR$ X±ÝXÃ_Æò³K˜ô’—÷i×äT.þ>ÞÇft¹¨{1êmƨ÷}ÑV¹H+×g•°‹½æ"Q‹lÌØ5éšËð¹f‹:~3rï¨e¶¨£Am!ÿé>tOޟ}þ|ò _›ÕÒµ VúÅÔÞð“{xã- Hederae helicis e folium created with maltodextrin as well as with SiO 2 – maltodextrin result in micellar solubilization. Oral use: Herbal medicinal product used as an expectorant in case of productive cough. This is possible owing to the unique set of substances contained in it such as large amount of saponins, flavonoids, phenolic acids and phytosterols as well as polyacetylenes and coumarins. The present study was conducted in the Thalisain block of Pauri Garhwal to document the medicinal plants used by the local communities. The use in children under 4 years of age is not recommended (see section 4.4 ‘Special warnings and precautions for use’). It was used in ancient Greece to … From the literature review to was also found that the plant has direct therapeutic effects on piles, dysentery, dyspepsia, diarrhea, vomiting, giddiness, worms, burning of the skin and menorrhoea. Hedera helix L., commonly known as ivy or English ivy, belongs to a family called Araliaceae. L., folium 1. The surface tension of aqueous solutions $- \Delta \gamma _{{\rm{sol}}}^{25}$ of Hederae helicis e folium extracts was determined according to the Polish Standard with stalagmometric method. Objective: Investigations were performed on model ivy leaf ( Hedera helix ) extracts which were created using a medium of diversified polarity ( ε M ). Kidneys were removed for histopathological examination. Hedera helix has a long history of medicinal use. The capacity of the β-lectin to bind to the Yariv artificial antigens was eliminated by progressive acid hydrolysis under conditions where both glycosidic and peptide linkages may be labile. , , , , , ,          , . Having recently spent several winter months in the dark and dripping Pacific Northwest in Oregon, I couldn’t help but ruminate on the English Ivy seemingly taking over everywhere and that this profuse plant must be intended for some herbal use. Conclusions: The use of the herbal medicine containing of ivy leaf dry extract administered twice a day may be a good alternative to current therapeutic regimens in the A number of existing studies in the broader literature have examined and proven the above-mentioned effects, scientifically [9, ... • Pretreatment groups included: T1, T2, T3, and T4, were orally treated with ivy leaf extract twice a day, every 12 hours for seven days with different doses (50, 100, 200 and 300 mg/kg). Gastrointestinal side effects with an incidence of 0.17% were the most important ones. S u m m a r y Hederae folium is used for the treatment of respiratory tract diseases with intense mucous formation, respiratory tract infections and in irritating cough which stems from common cold. Critical micellar concentration (cmc) was calculated. History; Medicinal Action and Uses---Parts Used---Leaves, berries.---Habitat---The plant is found over the greater part of Europe and Northern and Central Asia, and is said to have been particularly abundant at Nyssa, the fabled home of Bacchus in his youth.There are many varieties, but only two accepted species, i.e. The HMPC conclusions are taken into account by EU Member States when evaluating applications for the licensing of herbal medicines containing ivy leaf. The most used parts of the plant are its bark, leaves, and latex. It is hardy to zone (UK) 5 and is not frost tender. It is also native in western Asia and northern Africa. Future research should focus on evaluating the phytochemical, pharmacological, and toxicological properties of C. paniculata crude extracts as well as compounds isolated from the species. The mice were sacrificed under mild anesthesia and the blood samples were collected to titrate the levels of serum blood urea nitrogen (BUN), creatinine and, uric acid. (Apocynaceae) includes about 13 species and five subspecies widely distributed in South America, especially Brazil. The fruits of Hedera helix afforded, in addition to the known polyacetylenes falcarinone and falcarinol, a polyacetylenic epoxide closely related to panaxydol. Medicinal Uses: Collection: Recipes: Disease Cured: A climbing shrub, extensive climber on trees. molecules Article Time-dependent Inhibition of CYP2C8 and CYP2C19 by Hedera helix Extracts, A Traditional Respiratory Herbal Medicine Shaheed Ur Rehman 1, In Sook Kim 2, Min Sun Choi 2, Seung Hyun Kim 3, Yonghui Zhang 4 and Hye Hyun Yoo 2,* 1 Department of Pharmacy, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan; dr.shaheedmarwat@yahoo.com The prevalence of chronic obstructive respiratory disease, in particular chronic bronchitis (COPD), is increasing worldwide. To be specified for the individual finished product. Conclusions: Considering the favorable changes in all investigated clinical symptoms as well as the excellent tolerability in children and adults, the ivy leaf extract preparation Prospan acute Effervescent Cough Tablets can be considered as a therapeutic option in alleviating the symptoms of chronic bronchitis. The leaves of the plant are used to produce medicine. In-vivo studies of the drugs were compared in rabbit plasma with oral dosing. Methods: 7 adult Oryctolagus Caniculus rabbits were enrolled in this experiment. 5 Other constituents in the leaf include an alkaloid called emetine that is similar to one found in the herb tylophora. by Holly Nielsen June 2008. The Medicinal Herb English Ivy (Hedera helix) Traditional folk medicine used English ivy internally for liver, spleen and gallbladder disorders, and for gout , arthritis , rheumatism and dysentery. Well-established use Medicinal plants were widely used by, This research work was carried out to investigate the phytochemical constituents as well as the pharmacological prooperties of 'Bacopa monnieri'. For 2 hr incubation periods, saturated fatty acids are always more heavily labelled than mono-unsaturated fatty acids. Alcoholic extract of hedera helix dried leaves were prepared. Medicinal Ingredient: 7 mg/mL extract of dried ivy leaves (Hedera helix L.) Extraction ratio of 5-7.5:1 (7 mg is equivalent to 35 – 52.5 mg of dried ivy leaves). Results of a retrospective survey of 52,478 children (between 0 and 12 years) treated with alcohol-free cough syrup from dried ivy leaf extract, has confirmed the very good tolerability of the extract. 4.  Does anybody know what are the medicinal uses or any other ethnobotanical uses of Hedera helix ... Hedera helix subsp. Material and methods: A multicenter, observational survey was conducted by 268 doctors working in Primary Health Care. The major compounds responsible for the biological activity are triterpene saponins. During observation the percentage of children with intensive, very common, night and affected daily activities cough decreased significantly. Of the total plant species 49% were herbs, 26% trees, 23% shrubs and 2% climbers. The medicinal product should not be used longer than 4-5 days without medical advice. The survey was conducted during two routine, consecutive outpatient visits (including first supplemented retrospectively) resulting from the needs of therapy. Hedera helix is commonly known as English ivy. (Apocynaceae): Review. Phytochemical screening suggests terpenes and saponins as the possible anti-cancer agent in M. cordata. Due to their secretolytic and bronchospasmolytic effects, preparations from ivy leaves are mainly used in the treatment of respiratory diseases in children. Conclusions: Model extracts produced from Hederae helicis e folium with diversified polarity of the extraction medium (water – ethanol) are characterized by appropriate solubility of the components which results not only from the presence of chlorophyll and its derivatives in the extract but also from the technique used for spray drying of the extract. Scientific Name: Hedera helix L.. Family: Araliaceae. The species is hermaphrodite (has both male and female organs) and is pollinated by Bees, flies, Lepidoptera (Moths & Butterflies). Araliaceae. major sections of the community against common colds, cough, skin diseases, snake bite, fever, joint pains, bronchitis etc. The evolution of component fatty acids has been followed quantitatively in the reproductive apparatus of the Ivy plant (Hedera helix L.) during development of the fruit; pericarps and seeds are considered separately. Hedera helix . The antimicrobial investigation showed that ether extract showed antimicrobial activity against four bacteria and one fungus. One of the main stages in wound healing process is, the proliferative phase in which fibroblasts proliferate within the wounds and produce extracellular matrix. Herb: Ivy Latin name: Hedera helix Family: Araliaceae (Ginseng Family) Medicinal use of Ivy: Ivy is a bitter aromatic herb with a nauseating taste. It climbs by means of aerial rootlets with matted pads which cling strongly to the substrate. The powdered plant was successively extracted with ether solvent. The major phytochemical compounds isolated from this plant are steroidal saponins, proteins and carbohydrates. This date has been challenged by archaeologists and volcanologists/meteorologists, who moved the time of the eruption further into the autumn and eventually agreed to the final date 23–25 October. The phytochemical reports on this genus have revealed mainly triterpenes and iridoids. It is often used in folk herbal remedies, especially in the treatment of rheumatism and as an external application to skin eruptions, swollen tissue, painful joints, burns and suppurating cuts. Cluster analysis was performed to determine the relationships among the European ivy populations where the distribution in the dendrogram under the habitat specifity was found for the used iPBS marker. During preformulation studies attention was drawn to the possibility of micellar solubilization of cholesterol and selected structures of nonsteroidal anti-inflammatory drugs (NSAIDs) – ketoprofen. The time of the Vesuvius eruption, which perished Pompeii, Herculaneum and surrounding areas in ad 79, was initially set on the 24–25 August, based on written contemporary documents of the ancient historian Pliny the Younger. ªÙ¶ úÔq¯ˆV07²"è?\_.™\9C‰ŠYYQè¸8V6iٛZ™‘—U»é%$IÓkð˜>ÕÁ•ÏRéÂÞÜÝO«‚EmãÏiàOåõåúïn§šÈ¸B¤ŒÇµíÉ\?FÉó뛒ú'0Ùô_nó‰ÿŸ é/µ) These differences may be due to differential extraction of the β-lectin, degradative losses of protein or carbohydrate components of the β-lectin, or a combination of these possibilities. De Hedera helix, oftewel de klimop, komt in west en midden-Europa in het wild voor.De Hedera hibernica, oftewel de Atlantische klimop, vinden we vooral langs de kusten van Schotland, Ierland en Portugal.. De Hedera hibernica heeft een iets groter blad dan de Hedera helix. Fast Facts about Hedera Helix. Polyacetylenes from the fruits of Hedera helix, Dried Ivy Leaf Extract TRANSLATION Tolerability of dried ivy leaf extract in children, Alteration in the Composition of β-Lectins Caused by Chemical and Enzymic Attack, The diacetylene 11,12-dehydrofalcarinol from Hedera helix, Antitrypanosomial Activity of Some Saponins from Calendula arvensis, Hedera helix , and Sapindus mukurossi, Biosynthèse des acides gras au cours du développement du fruit et de la graine du Lierre, Behandlung chronischer Bronchitis mit einem Spezialextrakt aus Efeublättern – multizentrische Anwendungsbeobachtung mit 1350 Patienten, Phytochemical studies of species of the genus Leonurus. In 75.7%, productive cough was intense, in 61.6% it occurred at night, in 49.8% it was very common (several times per hour), and in 62.7% it affected daily activity. All rights reserved. Lurquin E, Swinnen I, Goossens A. Allergic contact dermatitis caused by Hedera helix arborescens and not by Hedera helix L. Contact Dermatitis. It is native of Africa. Hedera helix - mechanizm działania potwierdzony badaniami biologicznymi i biofizycznymi na modelu komórkowym. The structure of the epoxide was determined by spectral methods to be (Z)-9,10-epoxy-1-heptadecene-4,6-diyn-3-one. Very satisfied with a therapeutic effect of the preparation containing of ivy leaf dry extract administered twice a day were 68.2% of children guardians. This review emphasizes the phytochemical constituents and medicinal properties, which may help in future research. The Phytochemical screening of the extracts showed the presence of glycosides, alkaloids and flavonoids. This study is aimed at providing a critical review of the botany, biological activities, phytochemistry, and medicinal uses of C. paniculata. Jacques is a co mmon ornamental plant known as Spider plant. Hedera helix is an evergreen climbing plant, growing to Template:Convert high where suitable surfaces (trees, cliffs, walls) are available, and also growing as groundcover where no vertical surfaces occur. Pharmacological research revealed that C. paniculata extracts have analgesic, antibacterial, anticancer, anti-inflammatory, antiplasmodial, antiprotozoan, Aβ42 protein reduction, and cytotoxicity activities. We concluded that iPBS was very efficient in analysing the genetic diversity in Hedera helix , L. and that this marker can serve as a suitable tool to find genomically specific fingerprints relevant to the factors influencing the distribution of genetic variation. EMEA/HMPC/289432/2009. Wounds were treated with eucerin, phenytoin, hedera helix 10% and 20% eucerin-based creams for 20 days. The analysis revealed an unusually high amount of pollen from Hedera, an insect pollinated plant flowering from September to October in the area of Pompeii. Hedera helix . Helix hedera, or common ivy, is a familiar garden and houseplant to many people.Sometimes, ivy is used as a greenery decoration during the holidays, and an old Christmas carol “The Holly and The Ivy,” even bears the plant in its title. On day 21 (after the completion of the experiment), skin samples were taken and the collagen bundles in reticular and papillary layers of the dermis were evaluated histologically. A validated HPLC method was used for the analysis of blood plasma. Conclusion: This study can be used as prove of reading that ivy leaf extract might be used to prevent renal damage induced by paracetamol. Results: The study group consisted of 5162 patients treated for productive cough with the herbal medicine containing of ivy leaf dry extract administered twice a day. L., folium EMA/HMPC/325716/2017 Page 3/7 . NATURAL MEDICINE JOURNAL 4 Clearing Up the Cold and Flu Controversy ©2017 RESEARCH GUIDE Echinacea Echinacea refers to a group of plant species, which includes Echinacea purpurea, Echinacea angustifolia, and Echinacea pallida. Safety was evaluated by analyzing adverse events. Of these, 86% were polymorphic. Group A: as the control group, received NaCl 0.9%. No Skin irritation observed on rabbits. This enabled to evaluate the dependence $\Delta {\rm{G}}_{\rm{m}}^0 = 2.303$ RT×log cmc of the thermodynamic potential of micelle formation ( $\Delta {\rm{G}}_{\rm{m}}^0$ ). It is in leaf all year, in flower from October to November, and the seeds ripen from May to June. Pretreatment groups: included T1 (50 mg/kg), T2 (100 mg/kg), T3 (200 mg/kg), and T4 (300 mg/kg) which were treated with ivy leaf extract in different doses. How Hedera Helix is effective for various diseases is listed in repertory format. Besides of the ornamental applications, ivy is a very promising plant for medicinal use. inhibited proliferation of the MCF-7 cells via different mechanisms. In China, it is traditionally used in treatment of bronchitis, cough, f racture s; and burns. 1, 2. Habitat-related specifity of iPBS fingerprint in European populations of Hedera helix L. Histomorphometrical and Histopathological Evaluation of Hedera Helix Alcoholic Extract on Dermal Collagen Bundles, Protective effect of ivy leaf extract on paracetamol-induced oxidative stress and nephrotoxicity in mice, Formulation, characterization and in vivo evaluation of Hedera helix L., topical dosage forms, Identification of 3-O-β-D-glucopyranosyl-hederagenin from the leaves of Hedera helix. Maximal plasma concentration (c max) and the maximal time to reach c max (t max) were 70.226µg/mL, 75.26µg/mL and 2 hours for the micro emulsion and gel, 90.11µg/mL and 1 hour for the oral drug syrup respectively. 2012;66(6):352-3. List of various diseases cured by Hedera Helix. treatment of productive cough in children. Several Hedera species are used as herbal medicines for respiratory, skin problems, and other health-related conditions [25][26], ... Its structural formula is shown in Fig. Names of Hedera Helix in various languages of the world are also given. Access scientific knowledge from anywhere. Ivy leave extracts exhibit spasmolytic/antispasmodic, anti-inflammatory, antimicrobial, analgesic, anthelmintic, antitrypanosomial, antileishmanial, antitumor, antimutagenic, moluscocidal, antioxidant and antithrombin activities. This popular garden plant is also used for medicinal purposes. Risk profile Hedera helix extracts Page 1 of 17 Version date: 10th Feb 2012 RISK PROFILE Hedera Helix (Ivy) extracts CAS No.84082-54-2 Date of reporting 04.06.2012 Content of document ... approval (1988) of this herbal-medicinal use by the German Commission E, it has become one of the most popular prescribed herbal monopreparations in that country. Four wounds were created on each rabbit. E. purpurea has been studied most extensively, but the various forms of Echinacea contain Both parts of the reproductive apparatus are the sites of a very large accumulation of mono-unsaturated fatty acids during maturation. Ivy, Common Botanical: Hedera Helix (LINN.) Ethanol extract-vacuum liquid chromatography fractions, Chloropyhtum comosum (Thunb . ) EMEA 2011. Litogenolitic and solubility properties of products obtained from common ivy extract (Hederae helicis e folium) and medium of diversified polarity (εM), The herbal medicine containing of ivy leaf dry extract in the treatment of productive cough in children, Anti-inflammatory effects of Hederacoside-C on Staphylococcus aureus induced inflammation via TLRs and their downstream signal pathway in vivo and in vitro, A REVIEW OF BOTANY, THERAPEUTIC VALUE, PHYTOCHEMISTRY, AND PHARMACOLOGY OF CUSSONIA PANICULATA, Hederacoside-C Inhibition of Staphylococcus aureus-Induced Mastitis via TLR2 & TLR4 and Their Downstream Signaling NF-κB and MAPKs Pathways In Vivo and In Vitro, Pollen analysis of volcanic ash in Pompeian human skeletal remains. It has been observed as one of the best option of sustainable livelihoods for the residents of the area. International Research Journal of Pharmacy. Stability studies were performed for 3 months. This is a summary of the scientific conclusions reached by the Committee on Herbal Medicinal Products (HMPC) on the medicinal uses of ivy leaf. ex Schult. The major compounds responsible for the biological activity are triterpene saponins. The results showed that formulations were stable. The fatty acids which accumulate are principally petroselinic acid in the seed and cis-vaccenic and palmiltoleic acids in the pericarp. The research was conducted with data obtained from books about medicinal plants, theses, dissertations, and articles in refereed journals. -The genus Hedera refers to the true ivies (5), whereas many other plants are given the name “ivy” but do not belong to Hedera . Proving English Ivy: Hedera helix (Araliaceae’”Ginseng family). Hedera helix basic info. helix please link to them. Flowers yellowish-green, 5-merous. Introduction: Hedera helix is an evergreen plant used in treatment of wounds in the Iranian folk medicine. The project work reveals that the plant has antibacterial and antimutagenic activities. Hahn's self-branching. In Germany, it is estimated that 10-30% of adults have a COPD, whereby 15-20% of those affected experience current symptoms due to respiratory obstruction. L., folium . The ivy extract doses and the period of the treatment were selected based on previous reports (14), Research on the composition and activity of leonurus species, Mikania cordata is a medicinal plant traditionally used as an antibacterial, anti-ulcer, anti-inflammatory, antihelmintic and analgesic agent. Natural and planted European populations of ivy were analysed using an iPBS marker 5′ACCTGGCGTGCCA3′ with a total number of 238 fragments generated. Patients and Methods: The study included 1,350 male and female patients aged 4 years and above who were treated in one of 135 participating medical practices and who suffered from chronic bronchitis (with or without airway obstruction). The purpose of this study was to prepare topical formulations of micro emulsion, gel and ointment containing the Hedera helix L. extracts against asthma and to evaluate the physicochemical characteristics. Clinical trials on the efficacy and safety of dry ivy leaf extract have shown its high efficacy, comparable to synthetic medications, and better tolerance of herbal drugs. Women and local healers called vaids have a vital role in environmental management due to traditional knowledge and use of plants as medicine with undocumented knowledge. They stimulate the cough reflex irritating the sensory nerve endings in the gastric mucosa, which by way of the vagus testicles significantly increases secretion in the respiratory tract. Quality of life is clearly reduced and the reduction of mean life expectancy without adequate therapy is about 10 years (5). All these substances have been used in the production of cosmetic and medicinal preparations. So the aim of this study was to evaluate the effect of Hedera helix alcoholic extract on dermal collagen bundles in wound healing process. These fractions major compounds responsible for the biological activity are triterpene saponins not be used longer than days... ( DI ) and polymorphism information content ( PIC ) total number of 238 fragments generated helix cv of. And bronchospasmolytic effects, preparations from ivy leaves are mainly used in doses a. L. contact dermatitis tract disorders nearly 2000 years ago have been used in treatment of tract! This study aims to assess M. cordata as an anti-cancer agent has not been explored thus.. Of M. cordata as a possible anti-cancer agent, specifically against MCF-7 breast cancer cells Does! Properties for the residents of the epoxide was determined by spectral methods to be ( Z ) -9,10-epoxy-1-heptadecene-4,6-diyn-3-one oleic! 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